2-Butyl-4-Chloro-5-Formyl-1H-Imidazole (BCFI) Manufacturers in India
BCFI COMPOUNDS
2-Butyl-4-Chloro-5-Formyl-1H-Imidazole
- CAS No.: 83857-96-9
- Molecular formula: C₈H₁₁ClN₂O
- Molecular Weight: 186.64 g·mol⁻¹
- Therapeutic uses: Hypertension
- Specifications: Pharmaceutical intermediate grade
- Appearance: Off white to yellowish crystalline powder
- Storage: Room temperature (<25°C)
- Class: Pharmaceutical intermediate
Product overview
2-Butyl-4-Chloro-5-Formyl-1H-Imidazole (BCFI) is an intermediate employed in the synthesis of Losartan Potassium and other sartan-class APIs.
The compound is an imidazole-based building block used to enable controlled ring functionalization in downstream API synthesis when integrated into validated manufacturing workflows.
Key Applications of BCFI
Intermediate in Sartan Synthesis
Used as a precursor in the manufacture of Losartan Potassium and related sartan APIs; integration and yields depend on client process parameters.
Precursor for Imidazole-Derived APIs
Serves as a building block for other imidazole-structured pharmaceutical molecules across cardiovascular and metabolic therapy areas.
Research & Discovery
Used in medicinal chemistry and library synthesis for heterocyclic exploration where formyl and halo substituents enable further derivatisation.
Industrial Heterocyclic Synthesis
Adopted by chemical manufacturers for scalable synthesis of functionalised imidazole derivatives required in API and specialty chemical production.| Parameter | Details |
|---|---|
| Chemical Name | 2-Butyl-4-Chloro-5-Formyl-1H-Imidazole |
| Synonyms | BCFI; 2-Butyl-4-Chloro-5-Formylimidazole; 2-Butyl-5-Chloro-1H-Imidazole-4-Carboxaldehyde |
| CAS Number | 83857-96-9 |
| Molecular Formula | C₈H₁₁ClN₂O |
| Molecular Weight | 186.64 g·mol⁻¹ |
| Appearance | Off white to yellowish crystalline powder |
| Melting Point (Typical) | ~93–99°C |
Key Safety Information
- Use appropriate personal protective equipment (PPE) during handling
- Avoid inhalation of dust or direct skin/eye contact
- Handle in well-ventilated and controlled manufacturing environments
- Follow GMP-compliant material handling procedures
- Refer to Safety Data Sheet (SDS) for detailed handling and emergency guidance
Safety Precaution
- Handle only within certified pharmaceutical manufacturing facilities
- Ensure use of appropriate personal protective equipment (PPE) at all times
- Prevent direct exposure through inhalation, skin contact, or eye contact
- Maintain proper containment and follow established GMP protocols
- Dispose of material strictly in accordance with applicable regulatory and environmental guidelines
Frequently Asked Questions (FAQs)
BCFI (2-Butyl-4-Chloro-5-Formyl-1H-Imidazole) is the imidazole intermediate used to manufacture Losartan Potassium, one of the most commonly prescribed blood pressure medications. It’s also used as a building block for other imidazole-derived cardiovascular APIs.
CAS 83857-96-9, molecular formula C₈H₁₁ClN₂O, molecular weight 186.64 g/mol. These three data points are enough to verify a supplier’s quotation against your own material specifications.
Every shipment includes a batch-specific COA showing assay, appearance, and melting point (typically 93–99°C) against which you can verify the material on arrival. If your incoming QC doesn’t match the COA, PYG’s technical team will investigate the deviation directly.
Yes. Small sample quantities are available on request, subject to project qualification, so your lab can validate the material against your existing process before scaling to commercial volumes.
Reach out with your required volume for a specific lead time; it depends on batch scheduling and current order volume. Both sample-size and commercial bulk quantities can be accommodated, and the sales team will confirm MOQ and delivery timeline against your target date.
Yes, exports are handled subject to contractual terms and destination-country regulatory requirements. Share your destination country with the team and they’ll confirm the export documentation (COA, SDS, HS code, and any additional certificates) needed for smooth customs clearance.
Every batch is QC-tested before dispatch, but if a discrepancy is found on your end, the technical team investigates against the retained sample and COA and resolves it per standard quality-complaint protocol. Contact the team with your batch number for the fastest turnaround.
Need more information?
